Redirecting the flow of genetic information

RNA repair inspired by biology

At Tacit, our technology is inspired by the flow of genetic information. We repurpose naturally-existing systems to repair RNA, creating the most broadly-applicable and safest way to treat genetic disease.

RNA is the future and the potential is unbounded.

Splicing-Directed Repair™ technology fixes defective genes while avoiding the risks associated with other gene editing approaches.
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Delivering on the promise of gene therapy

Splicing-Directed Repair™ is the first broadly-applicable and non-immunogenic way to repair mutations. Our mission is to maximize the impact of our platform by developing treatments for tens of devastating illnesses.
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Team Tacit is bold

We’re a bold and creative team based in San Francisco, united by a desire to create a therapeutic platform that can change lives.
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Come build with us.